HEALTH:

Occasionally healthcare providers ask by patients during dispensing and prescribing about taking alcohol and other medicines.

This question makes thinking especially to the patients who take short-term medicines for acute diseases and patient who take long-term medicines with chronic diseases.

Most time, healthcare providers counseling patients by not taking alcohol and other medicines. And hence question to you: How quit alcohol for short-time during treatment? .You can answer this question  through email: rajabkhamis73@gmail.com or 0777 404277.

Alcohol refers to ethyl alcohol or ethanol. Alcohol is uses as chemical and medicine.

There are a large variety of alcoholic beverages likes, malted liquors ( obtained by fermentation of germinating cereals; are undistilled -alcohol contentis low( 3-6%) e.g. beers, stout. Now strong beers(up to 10%) are also available.

Wines Produced by fermentation of natural sugars as present in grapes and other fruits. This are also undistilled. E.g. effervescent wine champagne(12-16% alcohol),fortified wines e.g. port, sherry(alcohol 16-22%) and Spirits These are distilled after fermentation; e.g. Rum, Gin, Whiskey, Brandy, Vodka, e.t.c. Though the alcohol content of these can vary from 40-55%.

Alcohol effects vary according to the amount of food eaten of food eaten before drinking, the body weight or size of the person, experience in drinking, the mood and the setting, where the alcohol is taken.

Alcohol enters the blood stream rapidly as it does not need to be digested and it circulates to all parts of the body. Food in the stomach usually slows down the absorption of alcohol so it is good to eat before you drink.

Alcohol reaches the brain where it numbs judgment, impairs muscle co-ordination and control. Alcohol is broken down in the liver or eliminated through the lungs and the kidneys at rate of one unit of alcohol per hour. So a fifty kilogram person could consume one drink over a period of one hour and stay relatively sober. Drinking fast results in quicker intoxication.

Usually after the first sip of a drink, people are usually happy, talkative and socially relaxed, then gradually they drift into a state of being exited, emotionally less controlled and some of their bodily reactions are slowed down.

If drinking continues, the person may start to show signs of confusion and physically they will start to stagger, become disoriented, speech gets slurred and uncoordinated.

Also drinking may lead to stupor i.e. the person is unable to stand or walk but is still responsive when stimulated. The last stage is that of coma, which means the person becomes completely unconscious; breathing may stop leading to death.

Furthermore, 65% of all cases of liver damage are related to alcohol abuse, also neurological problems include peripheral neuropathy which affects about 10% of alcoholics. Epilepsy is seen in about 10% of alcoholics, peptic ulcers occurs in about 20% of alcoholics. Alcoholics  have an increased rate of suicide. Up to 10% of hospitalized alcoholics kill themselves.

Medicines interacts with alcohols are;

Alcohol synergises with anxiolytics, antidepressants, antihistaminics, hypnotics, opiods which marked central nervous system (CNS) depression with motor impairment can occur: Chances of accidents increase.

Individuals taking a sulfonylurea, cefoperazone, or metronidazole have experienced bizarre, somewhat disulfiram-like reactions when they consume alcohol. This reaction occurs only in some individuals and its basis is unclear. It passes off with time as alcohol is metabolized. Only reassurance and supportive treatment is needed.

Acute alcohol ingestion inhibits, while chronic intake intake induces CYP enzymes (especially CYP2E1). Formation of toxic metabolite of paracetamol (NAPQI) is increased in chronic alcoholics. Safe dose limit of paracetamol is lower in them. Metabolism of tolbutamide, phenytoin and some other drugs is similarly affected by acute and chronic alcohol intake.

Hypoglycemic action of insulin and sulfonylureas is enhanced by alcohol ingestion.

Aspirin and other NSAIDs cause more gastric bleeding when taken with alcohol.

Usually after the trip sip of a drink, people are usually happy, talkative and socially relaxed, then gradually they drift into a state of being exited, emotionally less controlled and some of their bodily reactions are slowed down.

Alcohol effects vary according to the amount of food ones eats, body weight, experience in drinking, the mood and the place alcohol is taken.

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